ENERGY LANDSCAPING FOR ANALYTICAL OPTIMIZATION: PROTEIN FOLDING PROBLEM

Authors

  • Temsiri Sapsaman King Mongkut’s University of Technology North Bangkok

Keywords:

Analytical Optimization, Energy Landscaping, Protein Folding

Abstract

Predicting the shape of an unknown protein, the protein folding problem is one of the most difficult global-optimization problems. Due to the complex energy landscape, locating the protein conformation with the lowest energy is a complicated and time-consuming process. This article presents the background of the protein folding problem, discusses its difficulty, and introduces a method of energy landscaping that improves the efficiency of the analytical optimization in the protein conformation prediction process.

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Issue

Vol. 2 No. 1 (2012): January-June 2555

Section

บทความวิจัย (Research Article)

License

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            The article has been published in Kasem Bundit Engineering Journal (KBEJ) is the copyright of the Kasem Bundit University. Do not bring all of the messages or republished except permission from the university.

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