ENERGY LANDSCAPING FOR ANALYTICAL OPTIMIZATION: PROTEIN FOLDING PROBLEM

Authors

  • Temsiri Sapsaman King Mongkut’s University of Technology North Bangkok

Keywords:

Analytical Optimization, Energy Landscaping, Protein Folding

Abstract

Predicting the shape of an unknown protein, the protein folding problem is one of the most difficult global-optimization problems. Due to the complex energy landscape, locating the protein conformation with the lowest energy is a complicated and time-consuming process. This article presents the background of the protein folding problem, discusses its difficulty, and introduces a method of energy landscaping that improves the efficiency of the analytical optimization in the protein conformation prediction process.

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Section

บทความวิจัย (Research Article)