Synbiotic Microencapsulation From Corn Dust in Alginate-Chitosan Capsules Improves Survival in Simulated Gastro-Intestinal Conditions


  • Nuttaporn Chanchay Maejo University Phrae Campus
  • Kornnikar Dittasuwannakul Maejo University Phrae Campus


simulated gastro-intestinal conditions, encapsulation, Lactobacillus acidophilus, Lactobacillus lactis


The research aims to study synbiotic microencapsulation from corn dust in alginate-chitosan capsules whether it improves survival in simulated gastro-intestinal conditions, by studying the survival of synbiotic made from a mixture of corn dust and two of strains probiotic microorganisms such as Lactobacillus acidophilus and Lactobacillus lactis which are not encapsulated and encapsulated in 2% of sodium alginate and coated with chitosan. The survival tested in simulated gastric juice (SGJ) shows that synbiotic with L. acidophilus encapsulated has the highest survival rate of 8.68%; moreover the synbiotic with L. lactis encapsulated has the highest survival rate of 5.43% resulting to L. acidophilus is more resistant to acidity than L. lactis. The survival test in simulated intestinal juice (SIJ) indicates that the survival rate of synbiotic with L. lactis encapsulated has the highest survival rate of 10.29%; in addition, synbiotic with L. acidophilus encapsulated has a survival rate of 5.86%. The difference of the synbiotic that are not encapsulated (p ≤ 0.05) when L. lactis will be resistant as well in bile salt. As a result, the survival rate is higher than the L. acidophilus when replication is in simulated intestinal juice allowing synbiotics can be used as animal feed.


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How to Cite

Chanchay, N., & Dittasuwannakul, K. (2021). Synbiotic Microencapsulation From Corn Dust in Alginate-Chitosan Capsules Improves Survival in Simulated Gastro-Intestinal Conditions. Creative Science, 13(3), 111–116. Retrieved from