Antioxidants activity and exhibit to stimulate immune cell production in in vitro of Hibiscus sabdariffa Linn. and Phyllanthus emblica L. extracts
Keywords:
Hibiscus sabdariffa Linn., Phyllanthus emblica L., Antioxidant, Anti-inflammation, Immune cell stimulation, Methanolic extractAbstract
Hibiscus sabdariffa Linn. and Phyllanthus emblica L. are widely used in traditional Thai medicine as natural remedies. The aim of this study was to investigate the total phenolics and flavonoids contents, antioxidant activities, NO inhibition and cytotoxicities of methanolic extracts. The result showed that H. sabdariffa Linn. and P. emblica L. extracts contain high amount of total phenolics and flavonoids contents which were related to the antioxidant activities. P. emblica L. extract showed to inhibit NO production in dose dependent manner. In addition, both extracts showed to stimulate the number of mouse macrophage cell line in the in vitro. These data suggest that H. sabdariffa Linn. and P. emblica L. extracts may be potentially beneficial in the treatment of inflammatory diseases through the inhibition of NO production as well as stimulation of immune system via increasing number of immunize cells.
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[8] B. Saad, Integrating traditional Greco-Arab and Islamic diet and herbal medicines in research and clinical practice, in: I. Ramzan (Eds.), Phytotherapies: Efficacy, safety and regulation, Wiley-Blackwell John Wiley & Sons, Inc., New Jersey, 2015, pp. 142 – 148.
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[11] N. Tlili, H. Mejri, F. Anouer, E. Saadaoui, A. Khaldi, N. Nasri, Phenolic profile and antioxidant activity of Capparis spinosa seeds harvested from different wild habitats, Ind Crops Prod. 76 (2015) 930 – 935.
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[13] D. Jang, G.A. Murrell, Nitric oxide in arthritis, Free Radic Biol Med. 24(9) (1998) 1511 – 1519.
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[16] C.M. Hogaboam, K. Jacobson, S.M. Collins, M.G. Blennerhassett, The selective beneficial effects of nitric oxide inhibition in experimental colitis, Am J Physiol Gastrointest Liver Physiol. 268(4) (1995) 673 – 684.
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Published
2018-12-27
How to Cite
wongklom, amornrat. (2018). Antioxidants activity and exhibit to stimulate immune cell production in in vitro of Hibiscus sabdariffa Linn. and Phyllanthus emblica L. extracts. Creative Science, 11(1), 18–25. Retrieved from https://ph01.tci-thaijo.org/index.php/snru_journal/article/view/136944
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Research Article
