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The objective of this study was to compare the effects of 5 Thai herbs on eradication of gastric-intestinal parasite in native chickens by flotation technique and simple sedimentation technique. The experiments were performed using a Randomized Complete Block Design with 6 treatments and 3 replications employing one chick per experimental unit compared by herbs such as Areca catechu Linn., Tamarindus indica Linn., Tinospora crispa Linn. Miers ex Hook.f.& Thomson and Momordica charantia Linn. plants in a bolus form with a conventional anthelmintic drug such as mebendazole (100 mg each). The results showed that sexing and the eggs per gran (EPG) were no difference significant (p>.05). The results indicated that O. paniculata had the effect on Ascaridia spp’s eggs (150.25 EPG) while M. charantia and T. indiga had the impact on Ascaridia spp’s eggs (116.9 and 66.9 EPG, respectively). These Thai herbs demonstrated a tendency of alternative treatment of helminthiasis in native chickens. This information might be beneficial for farmers to improve their animal production with lower cost and decrease the lost from gastric-intestinal parasites.