The incident and association of lactate and creatinine levels to septicemia among admitted patients in Thasala Hospital, Nakhon Si Thammarat Province

Abstract

This cross-sectional descriptive study aimed to investigate the incidence and correlation of creatinine and lactate levels with bloodstream infections (BSIs) among admitted patients at Tha Sala Hospital. The sample comprised 126 patients diagnosed with BSIs during admitted. Data were collected using a three aspect through collection form that included general information, laboratory results, and clinical characteristics. Descriptive statistics were used to analyze in demographics data, while chi-square tests were employed to assess relationships between variables. Multivariable logistic regression was used to identify sepsis predictors of in-hospital mortality. The result showed that the majority of participants were female in 51.59% and elderly patients aged over 60 years in 72.22%. Pneumonia was the leading cause of admitting in 44.44%. The average length of admitted was 11.32 days (S.D. = 10.31). Community-acquired infections were observed in 83.33%, and 37.30% had bloodstream infections. Gram-negative bacteria were the most common pathogens in 73.81%. The incidence rate was 140.5 per One hundred thousand population. The correlations of BSI included age, underlying disease, and length of admitted. For the associated with a higher risk of BSIs consists an increased creatinine levels more than >1.2 mg/dL (aOR=1.45, 95% CI = 1.53–3.47), respiratory tract infections (aOR=2.75, 95%CI=0.79–4.13) and gram-negative bacterial infections (aOR=2.51, 95%CI=1.07–6.81). However, lactate levels were not significantly associated with BSI. These findings suggest that respiratory infections, gram-negative bacterial infections, and elevated creatinine levels should be considered during patient management to mitigate the risk of BSIs in hospitalized patients