THE STUDY OF EFFICIENCY OF ACID FAST BACILLI STAIN AND MOLECULAR TECHNIQUE BY COMPARING WITH SPUTUM CULTURE FOR TB IN PULMONARY TUBERCULOSIS PATIENTS AT SAWANPRACHARAK HOSPITAL

Abstract

Early detection of pulmonary tuberculosis patients can reduce the spread of tuberculosis infection in the hospital. The aim of this retrospective study is to evaluate the efficiency of acid fast bacilli stain and molecular technique by comparing with sputum culture for TB of pulmonary tuberculosis patients in Sawanpracharak Hospital.  A total of 397 samples were collected during 1 January 2018 to 31 December 2018 to diagnose pulmonary tuberculosis in Medical Technology department Sawanpracharak Hospital, Nakhonsawan Province. The data were analyzed using descriptive statistics. It was found that the acid fast bacilli stain obtained sensitivity 94.3 %, specificity 94.2 %, positive predictive value and negative predictive value were 92.7 % and 95.5 %, respectively.   The molecular technique obtained sensitivity 100.0 %, specificity 93.7%, positive predictive value and negative predictive value were 92.6 % and 100.0 %, respectively. In concluded that the diagnosis of tuberculosis by acid fast bacilli stain and molecular technique are highly effective, can help find new patients faster, reduce the spread of infection, able to the correct treatment suitable and recover from tuberculosis.