Chemical Constituents from Glycosmis pentaphylla Stems

Abstract

Phytochemical investigation of the stems of Glycosmis pentaphylla led to the isolation of eleven known compounds, including bisglybomine B (1), glybomine B (2), carbalexin C (3), glycoborinine (4), skimmianine (5), robustine (6), -fagarine (7), arborinine (8), N-p-trans-coumaroyltyramine (9), 2-(N-methyl-2-phenylacetamido) benzoic acid (10) and (-)-syringaresinol (11). All structural assignments were made by comparing the NMR spectral data of the pure isolates with that published in the quoted literature. Among them, compound 10 was firstly purified as a natural product and compounds 10 and 11 were isolated from the genus Glycosmis for the first time. Some isolates were evaluated for anti-acetylcholinesterase activity.