Effects of Pikat Trisamo Extract on Antioxidant and Anti-inflammatory Activities
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Abstract
In this study were investigated the antioxidant and anti-inflammatory activities of Pikat Trisamo extracts, that including Terminalia chebula Retz., Terminalia arjuna Roxb. and Terminalia belerica Roxb. maceration with 95% ethanol. The results showed T. arjuna extracts had the highest antioxidant effects by DPPH assay with IC50 values was 4.89 ± 0.10 µg/mL, ABTS assay with IC50 values was 7.92 ± 0.15 µg/mL more than with standard Trolox IC50 values were 6.29 ± 0.07 and 10.96 ± 0.17 µg/mL and FRAP assay value was 787.46 ± 8.02 mmol FeSO4/g extract, respectively. T. arjuna had highest total phenolics and flavonoids content were 583.37 ± 11.15 mg GAE/g extract and 215.73 ± 3.06 mg QCE/g extract, respectively. Moreover, T. arjuna extracts can inhibit releasing of nitric oxide with IC50 value was 24.55 ± 0.53 µg/mL. The findings of this study indicated that the T. arjuna extract possesses the antioxidant and anti-inflammatory.
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