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This study investigated the extraction of lycopene from the Gac arils. The selection of suitable extraction solvent was firstly predicted using Hansen solubility parameters prediction. The suitable extraction conditions including Gac aril size powder, solvent to solid ratio, and extraction time were then determined. The prediction results revealed that the most suitable extraction solvent was ethyl acetate following by methyl acetate, ethanol, and methanol, respectively. The validation results also confirmed that ethyl acetate gave the highest lycopene yield (0.272 mg/g dried aril powder) compared with the others (0.250, 0.235, and 0.069 mg/g dried aril powder for methyl acetate, ethanol, and methanol, respectively.). The suitable extraction conditions were found to be 40 mesh of Gac aril size powder, 30:1(ml/g) of solvent to solid ratio, and 120 minutes of extraction time, giving lycopene content of 0.448 mg/g dried aril powder.
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Aissou, M., Chemat-Djenni, Z., Varón, E.Y., Fabiano, A.S., & Chemat, F. (2017). Limonene as an agro-chemical building block for the synthesis and extraction of bioactive compounds. Comptes Rendus Chimie, 20, 346-358. https://doi.org/10.1016/j.crci.2016.05.018
Akkarachaneeyakorn, S., Boonrattanakom, A., Pukpin, P., Rattanawaraha, S., & Mattaweewong, N. (2016). Extraction of aril oil from gac (momordica cochinchinensis spreng) using supercritical carbon dioxide. Journal of Food Processing and Preservation, 2, 1745-4549. http://doi:10.1111/jfpp.13122
Aoki, H., Kieu, N. T. M., Kuze, N., Tomisaka, K., & Chuyen, N. V. (2002). Carotenoid pigments in GAC fruit (Momordica cochinchinensis SPRENG). Bioscience, biotechnology, and biochemistry, 66(11), 2479-2482. https://doi.org/10.1271/bbb.66.2479.
Charles, H. (2007). Hansen solubility parameters a User’s Handbook. 2nd ed., Taylor & Francis Group, LLC.
Chuyen, H.V., Nguyen, M., Roach, P.D., Golding, J.B., & Parks, S. (2014). Gac fruit (Momordica cochinchinensis Spreng.): a rich source of bioactive compounds and its potential health benefits. International Journal of Food Science and Technology. http://doi:10.1111/ijfs.12721
Costa-Rodrigues, J., Pinho, O., & Monteiro, P.R.R. (2017). Can lycopene be considered an effective protection against cardiovascular disease? Food Chemistry. https://doi.org/10.1016/j.foodchem.2017.11.055
Do, T.V.T., Fan, L., Suhartini, W., & Girmatsion, M. (2019). Gac (Momordica cochinchinensis Spreng) fruit: A functional food and medicinal resource. Journal of Functional Foods, 62, 1756-4646. https://doi.org/10.1016/j.jff.2019.103512
Gerster, H. (1997). The potential role of lycopene for human health. Journal of the American College of Nutrition, 2, 109-126. http://10.1080/07315724.1997.10718661
Kubola, J., Meeso, N., & Siriamornpun, S. (2013). Lycopene and beta carotene concentration in aril oil of gac (Momordica cochinchinensis Spreng) as influenced by aril-drying process and solvents extraction. Food Research International, 50, 664-669. http://dx.doi.org/10.1016/j.foodres.2011.07.004
Le, A.V., Huynh, T. T., Parks, S.E., Nguyen, M.H., & Roach, P.D. (2018). Bioactive Composition, Antioxidant Activity, and Anticancer Potential of Freeze-Dried Extracts from Defatted Gac (Momordica cochinchinensis Spreng) Seeds. Medicines, 5, 104. http://dx.doi.org/10.3390/medicines5030104
Machmudah, S., Zakaria, Winardi, S., Sasaki, M., Goto, M., Kusumoto, N., & Hayakawa, K. (2012). Lycopene extraction from tomato peel by-product containing tomato seed using supercritical carbon dioxide. Journal of Food Engineering, 108, 290-296. http://dx.doi.org/10.1016/j.jfoodeng.2011.08.012
Saini, R.K., Rengasamya, K., Mahomoodally, F., & Keumc, Y.S. (2020). Protective effects of lycopene in cancer, cardiovascular, and neurodegenerative diseases: An update on epidemiological and mechanistic perspectives. Pharmacological Research, 155, 1043-6618. https://doi.org/10.1016/j.phrs.2020.104730
Shida, B.K., Turner, C., Charpman, M.H., & Mckeon, T.A. (2004). Fatty Acid and Carotenoid Composition of Gac (Momordica cochinchinensis Spreng) Fruit. Journal of agricultural and food chemistry, 2, 274-279. http://10.1021/jf030616i
Tran, X. T., Parks, S. E., Roach, P. D., Golding, J. B., & Nguyen, M. H. (2016). Effects of maturity on physicochemical properties of Gac fruit (M omordica cochinchinensis S preng.). Food science & nutrition, 4(2), 305-314. https://doi.org/10.1002/fsn3.291
United States Department of Agriculture; USDA. (2019). Taxon:Momordica cochinchinensis (Lour.) Spreng. U.S. National Plant Germplasm System. Agricultural Research Service, Germplasm Resources Information Network (GRIN-Taxonomy).
Van Krevelen, D. W., & Hoftyzer, P. J. J. (1976). Properties of Polymers: Their Estimation and Correlation with Chemical Structure. 2nd ed., Elsevier, Amsterdam.
Xianquan, S., Shi, J., Kakuda, Y., and Yueming, J. (2005) Stability of lycopene during food processing and storage. Journal of medicinal food. 4, 413–422. https://doi.org/10.1089/jmf.2005.8.413
Yara-Varón, E., Fabiano-Tixier, A.D., Balcells, M., Canela-Garayoa, R., & Bily, A. (2016). Is it possible to substitute hexane with green solvents for extraction of carotenoids A theoretical versus experimental solubility study? The Royal Society of Chemistry, 6, 27750-27759. https://doi.org/10.1039/C6RA03016E
Yuliani, S.H., Sandrapitaloka, A.S., Restiana, F.R., Aji, P.D.T., Gani, M.R., & Riswanto, F.D.O. (2019). Effects of particle size, extraction time, and solvent on daidzein yield extracted from tempeh. Jurnal Farmasi Sains dan Komunitas, 1, 44-49. https://doi.org/10.24071/jpsc.001794
Zuorro, A. (2020). Enhanced Lycopene Extraction from Tomato Peels by Optimized Mixed-Polarity Solvent Mixtures. Molecules, 25, 2038. http://dx.doi.org/10.3390/molecules25092038