Determination of Suitable Solvent and Extraction Conditions for Lycopene Isolation from Gac Fruit (Momordica Cochinchinensis Spreng.)

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Noppawan Motong
Panatpong Boonnoun
Suppakiet Saksuntor
Kittapat Sooknuan
Sornchai Thongsri


This study investigated the extraction of lycopene from the Gac arils. The selection of suitable extraction solvent was firstly predicted using Hansen solubility parameters prediction. The suitable extraction conditions including Gac aril size powder, solvent to solid ratio, and extraction time were then determined. The prediction results revealed that the most suitable extraction solvent was ethyl acetate following by methyl acetate, ethanol, and methanol, respectively. The validation results also confirmed that ethyl acetate gave the highest lycopene yield (0.272 mg/g dried aril powder) compared with the others (0.250, 0.235, and 0.069 mg/g dried aril powder for methyl acetate, ethanol, and methanol, respectively.). The suitable extraction conditions were found to be 40 mesh of Gac aril size powder, 30:1(ml/g) of solvent to solid ratio, and 120 minutes of extraction time, giving lycopene content of 0.448 mg/g dried aril powder.


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