Factors influencing the mortality of COVID-19 patients

Authors

  • Surfa Aphibalbae Division of Computational Science, Faculty of Science, Prince of Songkla University, Thailand
  • Nichanan Aksornchoo Division of Computational Science, Faculty of Science, Prince of Songkla University, Thailand
  • Klairung Samart Division of Computational Science, Statistics and Applications Research Unit, Faculty of Science, Prince of Songkla University, Thailand

Keywords:

Covid-19, Comorbidity, ROC-curve, Logistic regression

Abstract

COVID-19 has spread quickly throughout the world. The public health system has been significantly impacted by this pandamic. For people infected with COVID-19 who have comorbidity, this increases the severity of symptoms and increases the risk of mortality. The objective of this research was to characterize the COVID-19 patient and find the influence factors for the mortality of COVID-19 patients. The study population included COVID-19 cases collected between 14 February and 31 April 2020. Real-time data were collected from open-source COVID-19 repositories which collected data on 481,289 COVID-19 cases from 141 countries with a sample size of 1,143 people with complete data. The data were analyzed using descriptive statistics and inferential statistics. The Chi-square test or Fisher's exact test and multivariable logistic regression were used for identifying the factors associated with mortality in patients with COVID-19 and constructed ROC curves to determine the appropriate cut-off point to predict the chance of mortality in patients with COVID-19. The results found that five factors: Gender (OR=2.262 ; 95%CI= 1.519-3.367), Age (OR= 1.118 ; 95%CI= 1.102 - 1.134), Malignancy (OR= 0.193 ; 95%CI=0.039 - 0.949), Pneumonia (OR= 7.173 ; 95%CI= 2.818 - 18.254), and ARDS (OR=11.488 ; 95%CI=4.105 - 32.148) influenced the mortality of COVID-19 patients with percentage of correct predictions of 86%. Moreover, the sensitivity by ROC curve also showed very high accuracy.

 

Author Biographies

Surfa Aphibalbae, Division of Computational Science, Faculty of Science, Prince of Songkla University, Thailand

 

 

 

Nichanan Aksornchoo, Division of Computational Science, Faculty of Science, Prince of Songkla University, Thailand

 

 

 

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Published

2024-04-25

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