Allele Frequencies and Statistical Analysis of 15 Autosomal STR Loci of Myanmar Population in Thailand
Keywords:
Myanmarese population in Thailand, Autosomal STR, Allele frequency, Forensic geneticsAbstract
The aim of the present study is to investigate the allelefrequencies of 15 usingAutosomal Short Tandem Repeat (Autosomal STR) loci were established from 150 unrelated Myanmar Population in Thailand from the Central police forensic sciencedatabase. Allele frequencies were calculated from Autosomal STR markers which verified by AmpFlSTR Identifierplus PCR Amplification Kit (Thermo Fisher Scientific, USA) and Investigator IDplex GO kit (Qiagen, DEU). The results shown the allele frequencieswere calculated under Hardy-Weinberg equilibriumexcept D2S1338 and vWA. It is found the allele frequencies range from 0.0033 to 0.5333, heterozygosity ranged from 0.6267 to 0.8600, probability of identity from 0.0304 to 0.2081, and probability of paternity exclusion from 0.3753to 0.7494. The allele frequency and Genotype appearance of Myanmar populations in Thailand was compared with other countries including Myanmar population in China,AfricanAmerican, Caucasian, Hispanic and Asian by Fst and PCA analysis. The results demonstrated thatthere was the difference each population. This study is a powerful tool to be used as a reference in genetic forensic science.
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