TY - JOUR AU - Rujjanawate, Chaiyong PY - 2016/04/21 Y2 - 2024/03/29 TI - Treatment of tinea corporis with Tacca chantrieri's extract JF - Creative Science JA - Cre.Sci. VL - 8 IS - 1 SE - Research Article DO - UR - https://ph01.tci-thaijo.org/index.php/snru_journal/article/view/55331 SP - 115-121 AB - <span>Tinea corporis is usually treated by antifungal agents which are chemicals that are not produced<span>domestically and have to be imported. The use of indigenous herbs, if possible, would be a sustainable solution.<span>We therefore established a double blind study to evaluate a short term treatment of tinea corporis with the extract <span>of <span><em>Tacca chantrieri</em><span>, a local herb found in many parts of Thailand. Eighty patients were randomly selected to apply <span>tacca extract or the base solution alone for 14 days, and the lesions were periodically assessed on day 0, 7, 14 and <span>42. Each assessment consisted of clinical evaluation of redness, scaling and pruritus and direct microscopy <span>examination. The extract recipients showed significant clinical mycologic improvement beginning at day 7 through<br /><span>day 14. Microscopic examination of the skin scrapings showed negative results in all extract recipients on day 14. <span>Clinical evaluation and microscopic examination on day 42 indicated some mycologic infections in both control<br /><span>and test groups. It was concluded that the extract of <span><em>Tacca chantrieri </em><span>could be used as an effective agent to treat <span>tinea corporis. However, recurrent infections after the cessation of treatment are possible.<br /></span></span></span></span></span></span></span><br /></span></span></span></span></span></span></span></span> ER -