Determination of the Optimal Chemical Dosing Concentration in Reverse Osmosis Using Design of Experiments: A Case Study of Semiconductor Fabrication Factory in Chacheongsao, Thailand

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Siripan Sinluenam
Jintawat Chaichanawong


The objective of the study was to explore the effects of chemical dosage concentration with respectively to specification of treated Reverse Osmosis water and imply to simulate the optimal amount of chemical in the Reverse Osmosis (RO) process. The study was implied Water Treatment Plant in one semiconductor fabrication in Chacheongsao, Thailand as the case study. The experiment was conducted in the real pilot scale by variation of chemical concentration. Design of Experiment was used to evaluate in term of Analysis of Variance in order to validate the obtained result. Conductivity and % Salt Rejection are key performance indicators. The results developed the optimal range of treated chemical concentration of 10% Antiscalant with 10% Microbiocide solution with RO water conductivity in the range of 5.05-8.51 µS/cm with % Salt rejection in the range 95.12-98.52. The optimal condition could operate approximately to the calculated value from Excel Solver. This condition could reduce feeding chemical consumption amount and help monitoring performance of RO unit.


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